Statistical analysis
All calculations were performed with SPSS V.14.0 (SPSS Inc.)parisons between groups were performed using the Student’s t-test, ? 2 test and Fisher’s exact test, and the data were expressed as mean±SD for continuous variables. A p value of <0.05 was considered statistically significant.
Results
The new sufferers in the current data were 793 clients that have MP pneumonia and 384 people which have RWE inside the analysis months. For epidemiological comparison, a total 793 patients were datemyage used, as shown into the in the past authored article.fourteen To have health-related comparison between the teams, a maximum of 501 MP pneumonia patients that have been accepted throughout the the brand new previous epidemics (241 times in the 2007–2006, and you will 260 times last year), and 384 patients which have RWE were analysed (figure step 1). When you look at the study period, the level of acknowledge customers at the the agencies is a good full twenty five 911 (but nursery customers). There were everything 2100 acknowledge customers per year with a few distinctions when you look at the annually.
The majority of MP pneumonia customers had pursue-right up several months no less than 36 months regarding last crisis season off 2011, however the realize-up subjects pleased with our selection standards were 180 one of 501 times from the MP pneumonia class and you will 206 one of 384 times regarding the RWE category.
In the MP pneumonia patients, there were obvious episodes out-of times in the 2003, 2006–2007 and you may 2011, with circumstances occurring on the interepidemic symptoms. There were apparently regular variety of RWE cases from year to year during the research period. There are zero corresponding enhanced circumstances in MP pneumonia epidemic decades except during the 2007 (figure 2). Zero MP pneumonia patient who was simply readmitted because of MP reinfection across the epidemics try seen while in the study period. New indicate ages and you can ages shipments have been equivalent, while the height age groups had been 2–5 years of age in both teams (profile step three). In the seasonality off both teams, MP pneumonia are common inside the decreasing buy away from autumn, summer, winter and you may spring season, whenever you are patients having RWE was basically most commonplace in the autumn, followed closely by springtime, winter months and you may summer (studies maybe not shown).
Group and health-related functions from MP pneumonia and RWE organizations
Demographic, clinical and laboratory data in both groups are shown in table 1. The mean age and age distribution were similar in both groups as shown in figure 3 (5.4 years vs 5.6 years, p=0.312). Both groups had male predominance, and there were more males in the RWE group. As expected, cases with wheezing at presentation, the proportion of patients with history or family history of allergic diseases, and history of wheezing were higher in the RWE group. Recurrent wheezing after discharge was observed in 38 of 180 patients with MP pneumonia and 141 of the 206 patients with RWE (p<0.001).
In MP pneumonia patients, 52 of the total 501 patients (10.4%) had wheezing at presentation, 72 (14.4%) had a history of allergic diseases, 15 (3%) had RWE according to our definition and 40 (8%) had a family history of allergic diseases. When we divided the MP pneumonia patients into two groups of patients with wheezing (n=52) and without wheezing (n=449), the patients with wheezing were younger (3.7 years vs 5.6 years, p<0.001) and had higher proportions of history allergic diseases and wheezing history and higher values of leucocyte count and eosinophil differential (table 2). Among the 52 MP pneumonia patients with wheezing at admission, 10 were patient with RWE, while 42 had no previous RWE history. Thus, in this study, 66% (10 of 15) of patients with RWE history presented with wheezing, while 8.6% of patients without RWE history (42 of 486) had wheezing at presentation. In a follow-up study of patients who visited two or more times after discharge, 13 (including 5 cases of RWE) of 21 MP pneumonia patients with initial wheezing and 25 (including 2 cases of RWE) of 159 MP pneumonia patients without wheezing had at least one wheezing episode after discharge (table 2). Although not all patients were followed-up, it was estimated that at least 31 of the total MP pneumonia patients (n=501, 6.2%) showed a recurrent wheezing after initial MP infection.