Consumption regarding Potassium, Magnesium, Calcium, and you may Fiber and Chance of Heart attack Among us Males
On Divisions of Diet (An excellent.An effective., Age.B.Roentgen., Elizabeth.L.G., Yards.J.S., W.C.W.), Epidemiology (A great.A great., Age.B.R., Meters.A good.H., Meters.J.S., W.C.W.), and you can Health insurance and Public Decisions (We.K.), Harvard School away from Societal Health, as well as the Channing Lab, Agencies out of Drug, Harvard Medical College and you can Brigham and you may Ladies’ Healthcare (Age.B.Roentgen., Elizabeth.L.Grams., Yards.J.S., W.C.W., We.K.), Boston, Bulk.
Consumption of Potassium, Magnesium, Calcium, and you will Fiber and Danger of Heart attack In our midst People
Regarding Departments regarding Nutrients (A good.Good., Elizabeth.B.Roentgen., Elizabeth.L.G., Meters.J.S., W.C.W.), Epidemiology (An excellent.A beneficial., Age.B.Roentgen., M.An excellent.H., Meters.J.S., W.C.W.), and you will Health and Personal Conclusion (I.K.), Harvard College regarding Public Fitness, together with Channing Research, Agency off Drug, Harvard Scientific College or university and you will Brigham and you will Ladies’ Hospital (Age.B.R., E.L.Grams., Meters.J.S., W.C.W., We.K.), Boston, Mass.
Intake off Potassium, Magnesium, Calcium, and you may Dietary fiber and you may Risk of Coronary attack Among us Boys
On the Departments off Nutrition (An excellent.Good., Elizabeth.B.Roentgen., Elizabeth.L.Grams., M.J.S., W.C.W.), Epidemiology (An excellent.A., Elizabeth.B.R., M.A.H., M.J.S., W.C.W.), and you can Health and Personal Choices (We.K.), Harvard University of Social Fitness, as well as the Channing Lab, Service of Medicine, Harvard Medical School and you will Brigham and you will Women’s Healthcare (Elizabeth.B.R., Elizabeth.L.G., Yards.J.S., W.C.W., I.K.), Boston, Size.
Consumption out of Potassium, Magnesium, Calcium supplements, and you will Fibre and you can Chance of Stroke Among us Men
On Divisions regarding Nourishment (A good.A beneficial., E.B.Roentgen., Age.L.G., M.J.S., W.C.W.), Epidemiology (Good.A beneficial., Age.B.Roentgen., Meters.A beneficial.H., Yards.J.S., W.C.W.), and Health insurance and Public Conclusion (We.K.), Harvard College off Social Fitness, in addition to Channing Research, Service regarding Drug, Harvard Scientific College or university and you may Brigham and Ladies Medical (Elizabeth.B.R., E.L.G., Yards.J.S., W.C.W., I.K.), Boston, Bulk.
Intake from Potassium, Magnesium, Calcium supplements, and you will Fiber and you can Risk of Coronary attack In our midst Guys
On the Divisions off Nutrients (A good.A good., Elizabeth.B.Roentgen., Elizabeth.L.G., Yards.J.S., W.C.W.), Epidemiology (An excellent.Good., E.B.R., Yards.An effective.H., Meters.J.S., W.C.W.), and you will Health insurance and Societal Behavior (We.K.), 
Harvard School of Personal Health, and Channing Research, Service off Treatments, Harvard Medical University and you may Brigham and Ladies’ Medical (Elizabeth.B.R., Age.L.Grams., Meters.J.S., W.C.W., We.K.), Boston, Bulk.
Consumption of Potassium, Magnesium, Calcium supplements, and you will Fibre and you will Likelihood of Stroke In our midst Males
From the Departments out-of Diet (A great.A good., Age.B.Roentgen., E.L.Grams., Yards.J.S., W.C.W.), Epidemiology (A.An effective., Age.B.R., Yards.A.H., Yards.J.S., W.C.W.), and Health insurance and Public Conclusion (We.K.), Harvard College of Societal Wellness, and also the Channing Laboratory, Agencies regarding Medication, Harvard Medical School and you will Brigham and you will Ladies’ Hospital (E.B.R., Age.L.Grams., Meters.J.S., W.C.W., I.K.), Boston, Bulk.
Intake regarding Potassium, Magnesium, Calcium supplements, and Fibre and Risk of Coronary attack Among us Guys
On Divisions off Nutrients (A beneficial.A., Age.B.R., E.L.Grams., M.J.S., W.C.W.), Epidemiology (Good.A great., Elizabeth.B.Roentgen., Meters.An effective.H., M.J.S., W.C.W.), and you will Health insurance and Personal Choices (We.K.), Harvard School from Public Fitness, as well as the Channing Lab, Company off Treatments, Harvard Medical College and you may Brigham and Women’s Hospital (Elizabeth.B.Roentgen., E.L.G., Meters.J.S., W.C.W., I.K.), Boston, Mass.
Conceptual
Background-Animal tests and epidemiological research has advised one high potassium intake get slow down the likelihood of coronary arrest, nevertheless proof was inconclusive, and part out-of most other nourishment in the potassium-steeped edibles stays not familiar.
Measures and you can Results-We examined the fresh organization off potassium and you will related nutrition which have risk from heart attack certainly 43 738 United states guys, 40 so you can 75 years old, instead of diagnosed cardiovascular disorder or diabetes, exactly who accomplished good semiquantitative dinner regularity survey within the 1986. During the 8 many years of follow-upwards, 328 strokes (210 ischemic, 70 hemorrhagic, 48 unspecified) was reported. The newest multivariate cousin chance of heart attack of any type for males in the top fifth off potassium consumption (median consumption, 4.step 3 grams/d) instead of those who work in the base (average, dos.4 grams/d) try 0.62 (95% CI, 0.43, 0.88; P to possess trend=0.007). Results for ischemic coronary attack alone was basically comparable. Intakes off cereal soluble fiber and magnesium, however away from calcium supplements, was basically in addition to inversely on the chance of complete coronary arrest. Such inverse associations was all of the more powerful from inside the hypertensive than simply normotensive males and you may just weren’t materially changed from the adjustment to have blood pressure level. The means to access potassium drugs has also been inversely regarding risk of stroke, such certainly one of boys providing diuretics (cousin risk, 0.36; 95% CI, 0.18, 0.72).
Conclusions-Regardless if these data do not establish a beneficial causal relationships, he could be similar to the theory one dieting abundant with potassium, magnesium, and you can cereal fiber reduce the likelihood of coronary arrest, including one of hypertensive males. Potassium medicine could be of use, however, due to perils, fool around with should be carefully monitored and you will limited to people bringing potassium-shedding diuretics.